He graduated from the Department of Electrical Engineering at the University of Manchester in 1979 with Honours degree and received a Master degree in Information Technology and Telecommunications. He was awarded the PhD in Computer Science in 1983. Professor John Mantas began his academic career firstly at the University of Manchester and then at the National and Kapodistrian University of Athens.
He was Vice President of the Cyprus University of Technology and Dean of the School of Health Sciences; during his deanship he established in Cyprus the international Department of Public Health with the close collaboration of Harvard University and he has been President of the European Federation for Medical Informatics for the period 2010-2012 and Vice President of the International Medical Informatics Association for the European Region from 2012 to 2014.
As Working Group chair on Education Professor John Mantas led the initiative in providing the Educational Recommendations in Biomedical and Health Informatics. He is coordinator and partner in a number of national and European research programmes in the field of Health Informatics. He is a prolific writer and editor of fifteen books and of more than 250 papers in international journals and conferences. In 2016 he became Honorary Fellow of the European Federation for Medical Informatics.